This letter is about the use of artificial intelligence (AI) which is rapidly transforming the healthcare sector in the field of physical therapy. AI benefits could be enormous in terms of efficiency, individualized interventions, and clinical judgment based on evidence. In spite of the improvements, the problem of autonomy, data privacy, and the risk of algorithmic bias still remains alive. Strong ethical use and regulatory safeguards are needed. A human centered approach is necessary since the evidence shows that overreliance on automated machines may reduce the degree of therapeutic relationship, perceived empathy. The advances of AI will require joint collaboration among clinicians, engineers, data scientists, and ethicists.