Termination of unwanted pregnancies are one of the major health concerns throughout the world for women in their reproductive ages. Surgical abortions are very commonly performed worldwide and carry risks for complications, such as infection and trauma. Medical abortion, provides women with a safe alternative, and has also become a widely used alternative method of first trimester pregnancy termination for over twenty years. Less costly than surgery, it can be offered in simpler settings, without need for specialized equipment and by less- skilled providers and therefore provides more efficient use of clinic facilities and providers trained in surgical procedures. In this review, we will discuss this method, which can be used in primary care settings by family physicians, which is not yet available in Turkey for general use.